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Institute of Molecular Genetics and Genetic Engineering
Laboratory for Molecular Microbial Genetics and Ecology
Scientific field (Frascati Manual)
Environmental biotechnology
Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation
Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials
Biomaterials (as related to medical implants, devices, sensors)
Other natural sciences
Brief description of expertise
– The core expertise of our group is microbial molecular biology and ecology which we apply to a wide range of areas - Our research is interface of chemical and medicinal biotechnology - we have unique collection of Streptomyces and other soil actinomycetes and we continue our bioprospecting activities in search for novel bioactive microbial compounds and biotechnologically relevant enzymes - Biotechnology (offering sustainable and greener solutions to synthesis of valuable molecules and biomaterials including waste conversion to value-added materials) - Biocatalysis (discovery and engineering of novel biocatalysts for the production of chiral molecules, and improvement of biocatalytic processes) - Bioremediations (aromatic hydrocarbons, heavy metals…) and biodeteriorations (cultural heritage, paintings, books...) - Production and characterization of bioactive compounds (Streptomyces culture collection) - Novel approaches in antimicrobial treatments (microbial communication modulating molecules; virulence modulating agents; host-pathogen interactions; activity against microbial biofilms; antifungal therapy) - Taxonomic assessment of microbial communities using metagenomic approaches and taxonomic identification of bacterial isolates through 16S sequence analysis
Keywords
Microbiology , Biotechnology , Molecular Genetics, Biocatalysis, Bioremediations , Bacterial Secondary Metabolites , Biopolymers , Biofuels , Microbial diversity, Ecology
Commercial services
- Microbiological analysis of various samples (counts and taxonomic assessment) - Taxonomic identification of individual microbial isolates - Analysis and characterization of bioactive properties of new molecules (antimicrobial screens, in vitro cytotoxicity testing, quorum sensing, biofilms) - Assessment of embriotoxicity of compounds (zebrafish system) - Directed evolution of enzymes - PCR and sequencing - Analysis of biodegradability of novel materials - Training
Realized and current projects
TitleProject IDFunding sourceDuration
Microbial diversity study and characterization of beneficial environmental microorganisms173048Ministry of Education, Science and Technological Development2011-2015
Expression and regulation of pharmaceutically important genes in microorganisms 143056Ministry of Science and Environmental Protection2006-2010
TitleProject IDFunding sourceDuration
Structure-function studies of 16S rRNA methyltransferases: the basis of aminoglycoside antibiotic resistance and enzyme translational autoregulation  Wellcome Trust2006-2008
Search for new bioactive secondary metabolites Cooperation Between the Academy of Sciences of the Czech Republic and the Serbian Academy of Sciences and Arts2006-
Microbial diversity in the copper mine BorCRP/YUG09-03ICGEB2010-2012
Assessing and Monitoring Microbial Communities and their Impact on Documentary Heritage in Collection of National Library of Serbia – Preserving the Memory of the World (AMARCORD) Request number: 6651419001 SRB No. 590-2/2012UNESCO2012
Functionalisation of bacterial polymersBP2013Bioplastech Ltd., Dublin, Ireland2013-
Systems Biocatalysis (SysBiocat)COST Action CM1303COST2014-
Industry group (according to "Gazette RS", No. 54/10)
Manufacture of basic chemicals, fertilisers and nitrogen compounds, plastics and synthetic rubber in primary forms
Manufacture of pesticides and other agrochemical products
Manufacture of other chemical products
Manufacture of basic pharmaceutical products
Manufacture of plastic products
Manufacture of medical and dental instruments and supplies
Research and experimental development on natural sciences and engineering

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